Spinecare Topics

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Spine - Health and Disease
The Healing Spine

The Spine under Construction: Living and Remodeling Bone

The vertebrae of the spine finish growing at the approximate age of 25.  After this time many tissues of the spine continue to be replaced and remodeled.  Bone is a living tissue and is constantly being broken down and layed down.  The cells that make bone are referred to as osteoblasts.  The cells that dissolve or break bone down are referred to as osteoclasts. 

Bone is comprised of an infrastructure like the steel girders in a building.  The bony version of the steel girders is referred to as trabeculae.  The inside of the bone is somewhat similar in configuration to a honeycomb or a sponge with the connecting elements being the trabeculae.  The central portion of the bone has bone marrow.  The bone density within the center portion of the vertebral body is less than the exterior of the bone, which is referred to as the cortex.  The number of lattices within the bone is dependent on the balance between osteoblastic and osteoclastic function.  The balance between these cell groups is strongly influenced by the stresses placed upon the bone.  Up to 30-35 years age, the osteoblast and osteoclast function is balanced and the amount of bone created is generally equal to the amount broken down (reabsorbed).  After the age of 30-35 most individuals begin to lose bone density.  This is due to a greater amount of bone being resorbed rather than new bone being formed. 

Facet Joints

The synovial or free moving joints of the body are composed of a slippery surface (articular cartilage), a lubricating fluid (synovial fluid), and are held together by the joint capsule. The joint capsule is lined by the synovial membrane that consists of an inner most epithelial layer, lying on top of a layer of fat (adipose tissue). The synovial membrane produces the lubricating synovial fluid. The outer most layers of the joint capsule consists of dense connective tissue and ligaments.

Tissue Repair

Some tissues such as skin (surface epithelium) can grow back.  With more complex tissue relationships, the complex organization is seldom perfectly healed during the healing/regeneration process.
  • Impaired Healing
  • Impaired healing can have a variety of causes including:
  • Nutritional deficiencies
  • Inadequate blood supply
  • Presence of abnormal materials
  • Microorganisms.
  • Sutures
  • Foreign bodies.
  • Anti-inflammatory drugs such as Glucocorticoids (suppress inflammation, the first step in repair).
  • Recurrent microtrauma (overuse)

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Educational Partners

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To learn more about your spine. spinehealth, and available spinecare go to the International Spine Assocition (ISA) at www.spineinformation.org. The primary mission of the ISA is to improve spinehealth and spinecare through education. The ISA is committed to disseminating need-to-know information throught the World Wide Web in numerous languages covering many topics related to the spine, including information about spine disorders, spine heath, advances in technology and available spinecare



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All health information posted on the site is based on the latest research and national treatment standards, and have been written or reviewed and appoved by the American Acedemy of Spine Physicians and/or International Spine Association physicians or health professionals unless otherwise specified.



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